Hepatitis C Serology

Positive Hepatitis C Serology

When hepatitis C serology is positive, order HCV RNA to confirm active infection.

Chronic Hepatitis C (HCV RNA+)

For patients with current hepatitis C infection (HCV RNA+), follow these steps:

1. Report to Public Health - Contact AHS Communicable Disease Unit
2. Post-diagnosis counselling
3. Complete history - Risk factors, alcohol use, etc.
4. Physical exam - Signs of liver disease
5. Screen contacts
6. Vaccination - Refer for pneumococcal and hepatitis A/B vaccination if non-immune
7. Order abdominal ultrasound
8. Hepatology referral - All chronic hepatitis C patients should be seen to plan for treatment with direct-acting antivirals (DAAs)

Baseline Investigations

We usually order these baseline investigations:

• HCV genotyping
• Liver function tests
• CBC
• INR
• Hepatitis A and B serology

Referral Options in Calgary

• Hepatitis C Clinic at CUPS (Fax: 403-221-8785)
• Calgary Division of Gastroenterology & Hepatology Central Access & Triage (Fax: 403-944-6540)